Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability.

The tumor vascular effects of the tubulin destabilizing agent disodium combretastatinA-4 3-O-phosphate (CA-4-P) were investigated in the rat P22 tumor growing in a dorsal skin flap window chamber implanted into BD9 rats. CA-4-P is in clinical trial as a tumor vascular targeting agent. In animal tumo...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Tozer, G, Prise, V, Wilson, J, Cemazar, M, Shan, S, Dewhirst, M, Barber, P, Vojnovic, B, Chaplin, D
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2001