Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing.
Recent studies on the induction of erythropoietin gene expression by hypoxia have indicated that erythropoietin forms part of a widely operative system of gene regulation by oxygen. Similar responses to hypoxia, cobaltous ions and desferrioxamine have indicated that the action of these agents is clo...
المؤلفون الرئيسيون: | Gleadle, J, Ebert, B, Ratcliffe, P |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1995
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مواد مشابهة
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Induction of hypoxia-inducible factor-1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: evidence against a regulatory role for Src kinase.
حسب: Gleadle, J, وآخرون
منشور في: (1997) -
Mammalian oxygen sensing and hypoxia inducible factor-1
حسب: Wood, S, وآخرون
منشور في: (1997) -
Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin.
حسب: Ebert, B, وآخرون
منشور في: (1996) -
From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
حسب: Ratcliffe, P
منشور في: (2002) -
Oxygen regulated gene expression: erythropoietin as a model system.
حسب: Ratcliffe, P, وآخرون
منشور في: (1997)