Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase

Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase

Inactivation of opioid receptors limits the therapeutic efficacy of morphine-like analgesics and mediates the long duration of kappa opioid antidepressants by an uncharacterized, arrestin-independent mechanism. Here we use an iterative, discovery-based proteomic approach to show that following opioi...

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Bibliografiske detaljer
Main Authors:	Schattauer, SS, Land, BB, Reichard, KL, Abraham, AD, Burgeno, LM, Kuhar, JR, Phillips, PEM, Ong, SE, Chavkin, C
Format:	Journal article
Sprog:	English
Udgivet:	Nature Publishing Group 2017

Lignende værker

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