Targeting radiation-resistant hypoxic tumour cells through ATR inhibition
Background: Most solid tumours contain regions of sub-optimal oxygen concentration (hypoxia). Hypoxic cancer cells are more resistant to radiotherapy and represent the most aggressive fraction of a tumour. It is therefore essential that strategies continue to be developed to target hypoxic cancer ce...
主要な著者: | , , , , , , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2012
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