Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation.
An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of which are involved in fatty acid uptake. In vitro, both were induced by hypoxia in a hypoxia-inducible factor-1α (HIF-1α)-de...
Հիմնական հեղինակներ: | Bensaad, K, Favaro, E, Lewis, C, Peck, B, Lord, S, Collins, J, Pinnick, K, Wigfield, S, Buffa, F, Li, J, Zhang, Q, Wakelam, M, Karpe, F, Schulze, A, Harris, A |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Elsevier
2014
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Նմանատիպ նյութեր
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Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
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Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
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