Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation.

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation.

An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of which are involved in fatty acid uptake. In vitro, both were induced by hypoxia in a hypoxia-inducible factor-1α (HIF-1α)-de...

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Bibliografiske detaljer
Main Authors:	Bensaad, K, Favaro, E, Lewis, C, Peck, B, Lord, S, Collins, J, Pinnick, K, Wigfield, S, Buffa, F, Li, J, Zhang, Q, Wakelam, M, Karpe, F, Schulze, A, Harris, A
Format:	Journal article
Sprog:	English
Udgivet:	Elsevier 2014

Lignende værker

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