Pleiotropic effect of somatic mutations in the E2F subunit DP-1 gene in human cancer
Transcription factor E2F-1 and its interaction with pRb provide a key point of control in cell proliferation. E2F-1 participates in both cell cycle progression and apoptosis, and in cells exists with a DP dimerization partner protein, the most prominent being DP-1. By mining the tumor tissue and can...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Nature Publishing Group
2014
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