Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration

The HIV/AIDS pandemic is a major global health threat and understanding the detailed molecular mechanisms of HIV replication is critical for the development of novel therapeutics. To replicate, HIV-1 must access the nucleus of infected cells and integrate into host chromosomes, however little is kno...

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Bibliographic Details
Main Authors: Zhou, L, Sokolskaja, E, Jolly, C, James, W, Cowley, S, Fassati, A
Format: Journal article
Language:English
Published: Public Library of Science 2011
Subjects: