Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration
The HIV/AIDS pandemic is a major global health threat and understanding the detailed molecular mechanisms of HIV replication is critical for the development of novel therapeutics. To replicate, HIV-1 must access the nucleus of infected cells and integrate into host chromosomes, however little is kno...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2011
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Subjects: |