Long-lived memory CD8+ T cells are programmed by prolonged antigen exposure and low levels of cellular activation.

CD8+ T cells play a crucial role in controlling intracellular pathogens. The level of memory CD8+ T cells developing after vaccination or infection influences the degree of T cell-mediated protection after secondary infection. We used defined animal models and infections/immunizations by replicating...

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Bibliographic Details
Main Authors: Bachmann, M, Beerli, R, Agnellini, P, Wolint, P, Schwarz, K, Oxenius, A
Format: Journal article
Language:English
Published: 2006