Structure of the heterodimeric core primase.
Primases are DNA-dependent RNA polymerases that synthesize the oligoribonucleotide primers essential to DNA replication. In archaeal and eukaryotic organisms, the core primase is a heterodimeric enzyme composed of a small and a large subunit. Here we report a crystallographic and biochemical analysi...
Main Authors: | Lao-Sirieix, S, Nookala, R, Roversi, P, Bell, S, Pellegrini, L |
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Format: | Journal article |
Language: | English |
Published: |
2005
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