Structure of the heterodimeric core primase.

Primases are DNA-dependent RNA polymerases that synthesize the oligoribonucleotide primers essential to DNA replication. In archaeal and eukaryotic organisms, the core primase is a heterodimeric enzyme composed of a small and a large subunit. Here we report a crystallographic and biochemical analysi...

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Bibliographic Details
Main Authors: Lao-Sirieix, S, Nookala, R, Roversi, P, Bell, S, Pellegrini, L
Format: Journal article
Language:English
Published: 2005

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