Towards an engineered autologous cellular therapy for RAG2 deficiency

Towards an engineered autologous cellular therapy for RAG2 deficiency

<p>Severe combined immune deficiency (SCID) caused by RAG deficiency is a genetically-determined immune deficiency characterized by the virtual absence of adaptive immune cells. Unless treated with a hematopoietic stem cell transplantation (HSCT), RAG deficient patients succumb to severe infec...

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Dades bibliogràfiques
Autor principal:	Gardner, CL
Altres autors:	Acuto, O
Format:	Thesis
Idioma:	English
Publicat:	2020
Matèries:	Immunology Stem cells Immunotechnology Gene editing Immunotherapy Clinical immunology T cells

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