Towards an engineered autologous cellular therapy for RAG2 deficiency

Towards an engineered autologous cellular therapy for RAG2 deficiency

<p>Severe combined immune deficiency (SCID) caused by RAG deficiency is a genetically-determined immune deficiency characterized by the virtual absence of adaptive immune cells. Unless treated with a hematopoietic stem cell transplantation (HSCT), RAG deficient patients succumb to severe infec...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Gardner, CL
Awduron Eraill:	Acuto, O
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2020
Pynciau:	Immunology Stem cells Immunotechnology Gene editing Immunotherapy Clinical immunology T cells

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