Towards an engineered autologous cellular therapy for RAG2 deficiency
<p>Severe combined immune deficiency (SCID) caused by RAG deficiency is a genetically-determined immune deficiency characterized by the virtual absence of adaptive immune cells. Unless treated with a hematopoietic stem cell transplantation (HSCT), RAG deficient patients succumb to severe infec...
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Format: | Thesis |
Language: | English |
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2020
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