Alcohol consumption and telomere length: observational and Mendelian randomisation approaches

Alcohol consumption and telomere length: observational and Mendelian randomisation approaches

Alcohols impact on telomere length, a proposed marker of biological age, is unclear. We performed the largest observational study to date and compared findings with Mendelian randomization (MR) estimates. Two-sample MR used data from a recent genome-wide association study (GWAS) of telomere length....

Descripció completa

Dades bibliogràfiques
Autors principals:	Topiwala, A, Taschler, B, Ebmeier, KP, Smith, S, Zhou, H, Levey, DF, Codd, V, Samani, N, Gelernter, J, Nichols, TE, Burgess, S
Format:	Journal article
Idioma:	English
Publicat:	2021

Ítems similars

Alcohol consumption and telomere length: Mendelian randomization clarifies alcohol’s effects
per: Topiwala, A, et al.
Publicat: (2022)

Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: observational and mendelian randomization analyses
per: Topiwala, A, et al.
Publicat: (2022)

Telomere length and brain imaging phenotypes in UK Biobank
per: Topiwala, A, et al.
Publicat: (2023)

Association between cannabis use and brain structure and function: an observational and Mendelian randomisation study
per: Anya Topiwala, et al.
Publicat: (2024-11-01)

Impact of moderate alcohol consumption on brain iron and cognition: observational and genetic analyses
per: Topiwala, A, et al.
Publicat: (2022)

Causal inference on neuroimaging data with mendelian randomisation
per: Taschler, B, et al.
Publicat: (2022)

Alcohol consumption and MRI markers of brain structure and function: cohort study of 25,378 UK Biobank participants
per: Topiwala, A, et al.
Publicat: (2022)

Telomere length and brain imaging phenotypes in UK Biobank
per: Anya Topiwala, et al.
Publicat: (2023-01-01)

Telomere length and brain imaging phenotypes in UK Biobank.
per: Anya Topiwala, et al.
Publicat: (2023-01-01)

Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses.
per: Anya Topiwala, et al.
Publicat: (2022-07-01)

Causal inference on neuroimaging data with Mendelian randomisation
per: Bernd Taschler, et al.
Publicat: (2022-09-01)

Telomere length and metabolic syndrome traits: a Mendelian randomisation study
per: Loh, NY, et al.
Publicat: (2021)

Association between cannabis use and brain imaging phenotypes in UK Biobank: an observational and Mendelian randomization study
per: Ishrat, S, et al.
Publicat: (2023)

Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome
per: Ricardo Cortez Cardoso Penha, et al.
Publicat: (2023-04-01)

Alcohol consumption and MRI markers of brain structure and function: Cohort study of 25,378 UK Biobank participants
per: Anya Topiwala, et al.
Publicat: (2022-01-01)

Proteomic Mendelian randomization to identify protein biomarkers of telomere length
per: Jiaxuan Zhao, et al.
Publicat: (2024-09-01)

Effects of size at birth, childhood growth patterns and growth hormone treatment on leukocyte telomere length.
per: Carolina C J Smeets, et al.
Publicat: (2017-01-01)

Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study
per: Yingjian Deng, et al.
Publicat: (2022-10-01)

Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants.
per: Susanna C Larsson, et al.
Publicat: (2020-07-01)

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study.
per: Brunner, C, et al.
Publicat: (2016)

Moderate Alcohol Consumption and the Brain: Friend or Foe?
per: Topiwala, A
Publicat: (2016)

Peripheral blood leukocyte Telomere length and endometriosis: A Mendelian randomization study
per: Ying Wang, et al.
Publicat: (2024-07-01)

Casual effects of telomere length on sarcoidosis: a bidirectional Mendelian randomization analysis
per: Shiben Zhu, et al.
Publicat: (2024-07-01)

Causal relationship between immune cells and telomere length: mendelian randomization analysis
per: Yujian Li, et al.
Publicat: (2024-03-01)

Leukocyte Telomere Length and Cardiac Structure and Function: A Mendelian Randomization Study
per: Ahmed M. Salih, et al.
Publicat: (2024-02-01)

Association of shorter leucocyte telomere length with risk of frailty
per: Vasiliki Bountziouka, et al.
Publicat: (2022-06-01)

Investigating the impact of metabolic syndrome traits on telomere length: a Mendelian randomization study
per: Loh, N, et al.
Publicat: (2023)

A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism
per: Shiben Zhu, et al.
Publicat: (2025-01-01)

Leukocyte Telomere Length and Polycystic Ovary Syndrome: A Transethnic Mendelian Randomization Study
per: Lan Cao, et al.
Publicat: (2024-01-01)

Leukocyte telomere length and lung function: a mendelian randomization study in European population
per: Shenyu Zhu, et al.
Publicat: (2024-10-01)

Shorter telomere length increases the risk of lymphocyte immunodeficiency: A Mendelian randomization study
per: Bo Wang, et al.
Publicat: (2024-04-01)

Causal relationship between telomere length and sepsis: a bidirectional Mendelian randomization study
per: Jiamin Xu, et al.
Publicat: (2024-03-01)

Identifying effects of genetic obesity exposure on leukocyte telomere length using Mendelian randomization
per: Bangbei Wan, et al.
Publicat: (2023-03-01)

Leukocyte telomere length and sarcopenia-related traits: A bidirectional Mendelian randomization study
per: Dingkun Wang, et al.
Publicat: (2024-01-01)

Leukocyte telomere length and bipolar disorder risk: evidence from Mendelian randomization analysis
per: Likui Lu, et al.
Publicat: (2023-03-01)

Causal relationship between telomere length and epilepsy: A bidirectional Mendelian randomization study
per: Xinxin Luo, et al.
Publicat: (2023-12-01)

Risk relationship between leukocyte telomere length and constipation: a Mendelian randomization study
per: Zhenfei Chi, et al.
Publicat: (2023-09-01)

Mendelian randomization study on the causal relationship between leukocyte telomere length and prostate cancer.
per: Bangbei Wan, et al.
Publicat: (2023-01-01)

Causal relationships between telomere length and liver disease: a Mendelian randomization study
per: Shuangjing Zhu, et al.
Publicat: (2023-07-01)

Immune-mediated inflammatory diseases and leukocyte telomere length: A Mendelian randomization study
per: Meiling Liu, et al.
Publicat: (2023-04-01)