Active immunotherapy for chronic diseases.
With the effective control of infectious diseases in many parts of the world, chronic, non-communicable diseases have become the major cause of death and disability. Monoclonal antibodies (mAbs) have become an important class of drugs for the treatment of such diseases. Nevertheless, mAbs suffer fro...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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| _version_ | 1797101355434770432 |
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| author | Bachmann, M Whitehead, P |
| author_facet | Bachmann, M Whitehead, P |
| author_sort | Bachmann, M |
| collection | OXFORD |
| description | With the effective control of infectious diseases in many parts of the world, chronic, non-communicable diseases have become the major cause of death and disability. Monoclonal antibodies (mAbs) have become an important class of drugs for the treatment of such diseases. Nevertheless, mAbs suffer from major shortcomings in a chronic setting: most notably, generation of anti-antibodies and high cost of goods. Here, we discuss a novel approach to treat chronic diseases based on active rather than passive immunization and contrast the 2 treatment modalities to highlight their respective advantages and disadvantages. |
| first_indexed | 2024-03-07T05:50:42Z |
| format | Journal article |
| id | oxford-uuid:e8c90507-492e-4c68-958f-8035affe01b2 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:50:42Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:e8c90507-492e-4c68-958f-8035affe01b22022-03-27T10:49:15ZActive immunotherapy for chronic diseases.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e8c90507-492e-4c68-958f-8035affe01b2EnglishSymplectic Elements at Oxford2013Bachmann, MWhitehead, PWith the effective control of infectious diseases in many parts of the world, chronic, non-communicable diseases have become the major cause of death and disability. Monoclonal antibodies (mAbs) have become an important class of drugs for the treatment of such diseases. Nevertheless, mAbs suffer from major shortcomings in a chronic setting: most notably, generation of anti-antibodies and high cost of goods. Here, we discuss a novel approach to treat chronic diseases based on active rather than passive immunization and contrast the 2 treatment modalities to highlight their respective advantages and disadvantages. |
| spellingShingle | Bachmann, M Whitehead, P Active immunotherapy for chronic diseases. |
| title | Active immunotherapy for chronic diseases. |
| title_full | Active immunotherapy for chronic diseases. |
| title_fullStr | Active immunotherapy for chronic diseases. |
| title_full_unstemmed | Active immunotherapy for chronic diseases. |
| title_short | Active immunotherapy for chronic diseases. |
| title_sort | active immunotherapy for chronic diseases |
| work_keys_str_mv | AT bachmannm activeimmunotherapyforchronicdiseases AT whiteheadp activeimmunotherapyforchronicdiseases |