Transferrin and HFE genes interact in Alzheimer's disease risk: The Epistasis Project

Transferrin and HFE genes interact in Alzheimer's disease risk: The Epistasis Project

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Iron overload may contribute to the risk of Alzheimer's disease (AD). In the Epistasis Project, with 1757 cases of AD and 6295 controls, we studied 4 variants in 2 genes of iron metabolism: hemochromatosis (HFE) C282Y and H63D, and transferrin (TF) C2 and -2G/A. We replicated the reported inter...

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Détails bibliographiques
Auteurs principaux: Lehmann, D, Schuur, M, Warden, DR, Hammond, N, Belbin, O, Kölsch, H, Lehmann, MG, Wilcock, G, Brown, K, Kehoe, P, Morris, C, Barker, R, Coto, E, Alvarez, V, Deloukas, P, Mateo, I, Gwilliam, R, Combarros, O, Arias-Vásquez, A, Aulchenko, Y, Ikram, M, Breteler, M, van Duijn, C, Oulhaj, A, Heun, R
Format: Journal article
Langue:English
Publié: 2012

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