MacroD1 is a promiscuous ADP-ribosyl hydrolase localized to mitochondria

MacroD1 is a macrodomain containing protein that has mono-ADP-ribose hydrolase enzymatic activity toward several ADP-ribose adducts. Dysregulation of MacroD1 expression has been shown to be associated with the pathogenesis of several forms of cancer. To date, the physiological functions and sub-cell...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Agnew, T, Munnur, D, Crawford, K, Palazzo, L, Mikoč, A, Ahel, I
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Frontiers Media 2018