Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.

Show other versions (1)

Single nucleotide polymorphisms (SNPs) close to the VPS13C, C2CD4A and C2CD4B genes on chromosome 15q are associated with impaired fasting glucose and increased risk of type 2 diabetes. eQTL analysis revealed an association between possession of risk (C) alleles at a previously implicated causal SNP...

Full description

Bibliographic Details
Main Authors:	Mehta, Z, Fine, N, Pullen, T, Cane, M, Hu, M, Chabosseau, P, Meur, G, Velayos-Baeza, A, Monaco, A, Marselli, L, Marchetti, P, Rutter, G
Format:	Journal article
Language:	English
Published:	American Physiological Society 2016

Similar Items

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β cell are associated with glucose intolerance in humans and mice
by: Mehta, Z, et al.
Published: (2016)

Analysis of the human VPS13 gene family.
by: Velayos-Baeza, A, et al.
Published: (2004)

Dominant transmission of chorea-acanthocytosis with VPS13A mutations remains speculative.
by: Bader, B, et al.
Published: (2009)

Identification of VPS13C as a Galectin-12-binding protein that regulates Galectin-12 protein stability and adipogenesis
by: Yang, R, et al.
Published: (2016)

Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility
by: Yeshaw, WM, et al.
Published: (2019)

Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility
by: Wondwossen M Yeshaw, et al.
Published: (2019-02-01)

Drosophila Vps13 Is Required for Protein Homeostasis in the Brain
by: Vonk, JJ, et al.
Published: (2017)

Identification and analysis of the new, Vps13-like gene (V13LG) family that includes CHAC, the gene altered in chorea-acanthocytosis.
by: Velayos, A, et al.
Published: (2003)

Identification of a VPS13A founder mutation in French Canadian families with chorea-acanthocytosis.
by: Dobson-Stone, C, et al.
Published: (2005)

VPS13A and VPS13C Influence Lipid Droplet Abundance
by: Shuliang Chen, et al.
Published: (2022-09-01)

Corrigendum to “VPS13A and VPS13C Influence Lipid Droplet Abundance”
Published: (2023-05-01)

VPS13 Forum Proceedings: XK, XK-Related and VPS13 Proteins in Membrane Lipid Dynamics
by: Kevin Peikert, et al.
Published: (2023-02-01)

Identification of two compound heterozygous VPS13A large deletions in chorea-acanthocytosis only by protein and quantitative DNA analysis
by: Spieler, D, et al.
Published: (2020)

Identification of two compound heterozygous VPS13A large deletions in chorea‐acanthocytosis only by protein and quantitative DNA analysis
by: Derek Spieler, et al.
Published: (2020-09-01)

Vps13 is Required for Efficient Autophagy in
by: Yuchen Lei, et al.
Published: (2022-10-01)

Acinetobacter infection is associated with acquired glucose intolerance in burn patients.
by: Furniss, D, et al.
Published: (2005)

A Possible Role of VPS13B in the Formation of Golgi-Lipid Droplet Contacts Associating with the ER
by: Yuanjiao Du, et al.
Published: (2023-09-01)

Potential Effect of DPP-4 Inhibitors Towards Hepatic Diseases and Associated Glucose Intolerance
by: Sharma A, et al.
Published: (2022-06-01)

Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain
by: Esther García-García, et al.
Published: (2021-12-01)

The dyslexia-associated gene KIAA0319 encodes highly N- and O-glycosylated plasma membrane and secreted isoforms.
by: Velayos-Baeza, A, et al.
Published: (2008)

Alternative splicing in the dyslexia-associated gene KIAA0319.
by: Velayos-Baeza, A, et al.
Published: (2007)

Targeting Copper Homeostasis Improves Functioning of <i>vps13</i>Δ Yeast Mutant Cells, a Model of <i>VPS13</i>-Related Diseases
by: Piotr Soczewka, et al.
Published: (2021-02-01)

The dyslexia-associated protein KIAA0319 interacts with adaptor protein 2 and follows the classical clathrin-mediated endocytosis pathway.
by: Levecque, C, et al.
Published: (2009)

Double Trouble Myotonic Dystrophy Type-1 and Parkinson Syndrome Associated with Variants in SYNJI, VPS13C, and DNAJC6
by: Josef Finsterer
Published: (2023-01-01)

Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface
by: Elisa Fagnani, et al.
Published: (2024-12-01)

Glucose intolerance in intensive care patients: Incidence and outcome
by: Ahmed A. El Shebiny, et al.
Published: (2021-01-01)

The Vps13 Family of Lipid Transporters and Its Role at Membrane Contact Sites
by: Samantha Katarzyna Dziurdzik, et al.
Published: (2021-03-01)

Blueberries’ Impact on Insulin Resistance and Glucose Intolerance
by: April J. Stull
Published: (2016-11-01)

Prognosis of Pregnancies with Different Degrees of Glucose Intolerance
by: Sevgi Ayhan, et al.
Published: (2016-05-01)

Risk factors for glucose intolerance in active acromegaly
by: Kreze A., et al.
Published: (2001-01-01)

The dyslexia-associated KIAA0319 protein undergoes proteolytic processing with {gamma}-secretase-independent intramembrane cleavage.
by: Velayos-Baeza, A, et al.
Published: (2010)

Increasing Expiratory Hydrogen in Lactose Intolerance Is Associated with Additional Food Intolerance/Malabsorption
by: Wolfgang J. Schnedl, et al.
Published: (2020-11-01)

Glucagon hypersecretion underlies glucose intolerance in CAPS-deficient mice
by: Speidel, D, et al.
Published: (2006)

Flavonoids as Potential Drugs for <i>VPS13</i>-Dependent Rare Neurodegenerative Diseases
by: Piotr Soczewka, et al.
Published: (2020-07-01)

The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus
by: Damian Kolakowski, et al.
Published: (2021-11-01)

A VPS13B mutation in Cohen syndrome presented with petechiae: An unusual presentation
by: Alireza Razavi, et al.
Published: (2021-07-01)

Deletion as novel variants in VPS13B gene in Cohen syndrome: Case series
by: Kang Li, et al.
Published: (2023-09-01)

Bombyx mori Vps13d is a key gene affecting silk yield.
by: Luochao Zhao, et al.
Published: (2022-01-01)

TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation.
by: Hall, B, et al.
Published: (2006)

SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice
by: Tomoya Mizumoto, et al.
Published: (2022-11-01)