Once- versus twice-daily abacavir and lamivudine in African children: the randomised controlled ARROW Trial

Background: Antiretroviral therapy (ART) adherence is critical for successful HIV treatment outcomes. Once-daily dosing could improve adherence. Plasma concentrations of once-daily vs twice-daily abacavir + lamivudine are bioequivalent in children, but no randomized trial has compared virological ou...

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Main Authors: Musiime, V, Kasirye, P, Naidoo-James, B, Nahirya-Ntege, P, Mhute, T, Cook, A, Mugarura, L, Munjoma, M, Thoofer, N, Ndashimye, E, Nankya, I, Spyer, M, Thomason, M, Snowden, W, Gibb, D, Walker, A, ARROW Trial Team
格式: Journal article
出版: Lippincott, Williams and Wilkins 2016