A protective monoclonal antibody targets a site of vulnerability on the surface of Rift Valley fever virus
The Gn subcomponent of the Gn-Gc assembly that envelopes the human and animal pathogen, Rift Valley fever virus (RVFV), is a primary target of the neutralizing antibody response. To better understand the molecular basis for immune recognition, we raised a class of neutralizing monoclonal antibodies...
Main Authors: | Allen, ER, Krumm, SA, Raghwani, J, Halldorsson, S, Elliott, A, Graham, VA, Koudriakova, E, Harlos, K, Wright, D, Warimwe, GM, Brennan, B, Huiskonen, JT, Dowall, SD, Elliott, RM, Pybus, OG, Burton, DR, Hewson, R, Doores, KJ, Bowden, TA |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2018
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