Investigating the substrate selectivity and the inhibitor of the human KDM7 sub-family of JmjC histone lysine demethylases

<p>The regulation of gene expression by the post-translational modifications (PTMs) of histone tails is important in eukaryotic cell biology and of current medical interest. Specific PTMs to histone tails, including acetylation, phosphorylation and methylation, can either promote or inhibit...

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Bibliographic Details
Main Author: Zhang, Y
Other Authors: Schofield, C
Format: Thesis
Published: 2019

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