A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases.
Histone methylations are important chromatin marks that regulate gene expression, genomic stability, DNA repair, and genomic imprinting. Histone demethylases are the most recent family of histone-modifying enzymes discovered. Here, we report the characterization of a small-molecule inhibitor of Jumo...
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Bibliographic Details
| Main Authors: |
Luo, X,
Liu, Y,
Kubicek, S,
Myllyharju, J,
Tumber, A,
Ng, S,
Che, K,
Podoll, J,
Heightman, T,
Oppermann, U,
Schreiber, S,
Wang, X |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2011
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