STUDIES ON THE EXCHANGE OF VALINE-OXYGEN DURING THE BIOSYNTHESIS OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE

STUDIES ON THE EXCHANGE OF VALINE-OXYGEN DURING THE BIOSYNTHESIS OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE

Incorporation of [4-2H6,18O2]-valine into δ-(L)-α-aminoadipoyl)-L-cysteinyl-D-valine (ACV), by intact cells of Cephalosporium acremonium, demonstrated the intracellular exchange of one and both valine oxygen atoms. Incubation of [18O2]-valine with the purified ACV synthetase from C. acremonium gave...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Baldwin, J, Adlington, R, Bird, J, Field, R, Ocallaghan, N, Schofield, C
Format:	Journal article
Sprache:	English
Veröffentlicht:	1992

Ähnliche Einträge

EXCHANGE OF VALINE-OXYGEN DURING THE BIOSYNTHESIS OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE
von: Baldwin, J, et al.
Veröffentlicht: (1991)

EXCHANGE OF THE VALINE-2-H IN THE BIOSYNTHESIS OF L-DELTA-(ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE
von: Baldwin, J, et al.
Veröffentlicht: (1993)

AN EFFICIENT SUBSTITUTE FOR THE ALPHA-AMINOADIPOYL MOIETY OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE IN THE ENZYMATIC-SYNTHESIS OF PENICILLINS
von: Baldwin, J, et al.
Veröffentlicht: (1987)

L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine synthetase: thioesterification of valine is not obligatory for peptide bond formation.
von: Shiau, C, et al.
Veröffentlicht: (1997)

Delta-L-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase: isolation of L-cysteinyl-D-valine, a 'shunt' product, and implications for the order of peptide bond formation.
von: Shiau, C, et al.
Veröffentlicht: (1995)

Molecular mechanism of the multifunctional enzyme L-delta(alpha-aminoadipoyl)-L-cysteinyl-D-valine (ACV) synthetase
von: Shiau, C, et al.
Veröffentlicht: (1995)

Molecular mechanism of the multifunctional enzyme L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine (ACV) synthetase.
von: Shiau, C, et al.
Veröffentlicht: (1995)

delta-L-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase: the order of peptide bond formation and timing of the epimerisation reaction.
von: Shiau, C, et al.
Veröffentlicht: (1995)

Substrate specificity of L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase from Cephalosporium acremonium: demonstration of the structure of several unnatural tripeptide products.
von: Baldwin, J, et al.
Veröffentlicht: (1994)

THE FATE OF VALINE-OXYGEN DURING PENICILLIN BIOSYNTHESIS
von: Baldwin, J, et al.
Veröffentlicht: (1989)

Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine.
von: Long, A, et al.
Veröffentlicht: (2005)

CEPHALOSPORIN-C BIOSYNTHESIS - STEREOCHEMISTRY OF THE INCORPORATION OF D,L,D-ALPHA-AMINODIPOYL-CYSTEINYL-(3S)-[2-2H,4-C-13]VALINE INTO BETA-LACTAM COMPOUNDS
von: Baldwin, J, et al.
Veröffentlicht: (1989)

THE SYNTHESIS OF ARYL SUBSTITUTED ANALOGS OF PHENOXYACETYL-L-CYSTEINYL-D-VALINE AND PHENYLACETYL-L-CYSTEINYL-D-VALINE - APPLICATION TO THE PHOTOAFFINITY-LABELING OF ISOPENICILLIN N SYNTHETASE
von: Baldwin, J, et al.
Veröffentlicht: (1987)

Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate.
von: Long, A, et al.
Veröffentlicht: (2003)

The crystal structure of isopenicillin N synthase with δ-((L)-α-aminoadipoyl)-(L)-cysteinyl-(D)-methionine reveals thioether coordination to iron.
von: Clifton, I, et al.
Veröffentlicht: (2011)

Isopenicillin N synthase binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine through both sulfur atoms.
von: Clifton, I, et al.
Veröffentlicht: (2011)

Analysis of the conversion of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alpha-aminobutyrate by active-site mutants of Aspergillus nidulans isopenicillin N synthase.
von: Rowe, C, et al.
Veröffentlicht: (1998)

Terahertz Sensing of L-Valine and L-Phenylalanine Solutions
von: Jingyi Shu, et al.
Veröffentlicht: (2024-06-01)

Substrate analogues and inhibition of ACC oxidase: Conversion of D-valine to iso-butanal
von: Gibson, E, et al.
Veröffentlicht: (1998)

Valine in diets for Nile tilapia
von: Rômulo Batista Rodrigues, et al.

Conformational Studies of ε- CBz- L- Lysine and L- Valine Block Copolypeptides
von: Ajay Kumar
Veröffentlicht: (2010-01-01)

The interaction of isopenicillin N synthase with homologated substrate analogues δ-(L-α-aminoadipoyl)-L-homocysteinyl-D-Xaa characterised by protein crystallography.
von: Daruzzaman, A, et al.
Veröffentlicht: (2013)

The Role of Chirality and Helicity between d- and l-Valine Optical Lattices
von: Jingjing Li, et al.
Veröffentlicht: (2018-07-01)

Effects of L-valine in layer diets containing 0.72% isoleucine.
von: Usman Liaqat, et al.
Veröffentlicht: (2022-01-01)

Effects of L-valine in layer diets containing 0.72% isoleucine
von: Usman Liaqat, et al.
Veröffentlicht: (2022-01-01)

Modelling of L-valine Repeated Fed-batch Fermentation Process Taking into Account the Dissolved Oxygen Tension
von: Tzanko Georgiev, et al.
Veröffentlicht: (2009-03-01)

Conformational Studies on γ - Benzyl- L- Glutamate and L- Valine Containing Block Copolypeptides
von: Ajay Kumar
Veröffentlicht: (2010-01-01)

Engineering Escherichia coli for autoinducible production of L-valine: An example of an artificial positive feedback loop in amino acid biosynthesis.
von: Natalia V Geraskina, et al.
Veröffentlicht: (2019-01-01)

PROTISKAI ATSILIKUSIŲ MOKINIŲ VALINES VEIKLOS VYSTYMOSI KLAUSIMU
von: J. Laužikas
Veröffentlicht: (2016-01-01)

Effect of valine on 5-HT neurotransmission and mood.
von: Cowen, P, et al.
Veröffentlicht: (1996)

Rochelle (La) (Charente-Maritime). Square Valin
von: Emmanuel Barbier
Veröffentlicht: (2017-12-01)

The biological functions and metabolic pathways of valine in swine
von: Chuni Wang, et al.
Veröffentlicht: (2023-10-01)

Half-life of Fructosyl-valine in the Plasma of Chicks
von: Natsuki Takahashi, et al.
Veröffentlicht: (2020-01-01)

Valine metabolites analysis in ECHS1 deficiency
von: Mari Kuwajima, et al.
Veröffentlicht: (2021-12-01)

Time Series Analysis of Fed-batch Fermentation Process for L-valine Production
von: Tzanko Georgiev, et al.
Veröffentlicht: (2006-04-01)

THE ROLE OF ALPHA-KETOGLUTARATE IN CEPHALOSPORIN BIOSYNTHESIS
von: Baldwin, J, et al.
Veröffentlicht: (1989)

Effect of Solvent on Protonation Equilibria of L-Proline and L-Valine in 1, 2-Propanediol-Water Mixtures
von: P. Bhushanavathi, et al.
Veröffentlicht: (2012-01-01)

Valine biosynthesis in Saccharomyces cerevisiae is regulated by the mitochondrial branched-chain amino acid aminotransferase Bat1
von: Natthaporn Takpho, et al.
Veröffentlicht: (2018-03-01)

THE ROLE OF MOLECULAR-OXYGEN IN CEPHALOSPORIN-C BIOSYNTHESIS
von: Baldwin, J, et al.
Veröffentlicht: (1987)

Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents.
von: Oltenfreiter, R, et al.
Veröffentlicht: (2006)