Importance of collection tube during clinical studies of oseltamivir.
Ex vivo conversion of the anti-influenza drug oseltamivir to its active metabolite can be inhibited by the esterase inhibitor dichlorvos or by using commercial fluoride-oxalate tubes. Oseltamivir and its active metabolite remain intact in plasma samples during a proposed virus heat inactivation step...
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Bibliographic Details
| Main Authors: |
Lindegardh, N,
Davies, G,
Hien, T,
Farrar, J,
Singhasivanon, P,
Day, N,
White, N |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2007
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