Importance of collection tube during clinical studies of oseltamivir.
Ex vivo conversion of the anti-influenza drug oseltamivir to its active metabolite can be inhibited by the esterase inhibitor dichlorvos or by using commercial fluoride-oxalate tubes. Oseltamivir and its active metabolite remain intact in plasma samples during a proposed virus heat inactivation step...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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| _version_ | 1826302752831045632 |
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| author | Lindegardh, N Davies, G Hien, T Farrar, J Singhasivanon, P Day, N White, N |
| author_facet | Lindegardh, N Davies, G Hien, T Farrar, J Singhasivanon, P Day, N White, N |
| author_sort | Lindegardh, N |
| collection | OXFORD |
| description | Ex vivo conversion of the anti-influenza drug oseltamivir to its active metabolite can be inhibited by the esterase inhibitor dichlorvos or by using commercial fluoride-oxalate tubes. Oseltamivir and its active metabolite remain intact in plasma samples during a proposed virus heat inactivation step: incubation at 60 degrees C for 45 min. |
| first_indexed | 2024-03-07T05:52:18Z |
| format | Journal article |
| id | oxford-uuid:e94fa061-a72c-428d-a227-c14562569e5d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:52:18Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:e94fa061-a72c-428d-a227-c14562569e5d2022-03-27T10:53:18ZImportance of collection tube during clinical studies of oseltamivir.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e94fa061-a72c-428d-a227-c14562569e5dEnglishSymplectic Elements at Oxford2007Lindegardh, NDavies, GHien, TFarrar, JSinghasivanon, PDay, NWhite, NEx vivo conversion of the anti-influenza drug oseltamivir to its active metabolite can be inhibited by the esterase inhibitor dichlorvos or by using commercial fluoride-oxalate tubes. Oseltamivir and its active metabolite remain intact in plasma samples during a proposed virus heat inactivation step: incubation at 60 degrees C for 45 min. |
| spellingShingle | Lindegardh, N Davies, G Hien, T Farrar, J Singhasivanon, P Day, N White, N Importance of collection tube during clinical studies of oseltamivir. |
| title | Importance of collection tube during clinical studies of oseltamivir. |
| title_full | Importance of collection tube during clinical studies of oseltamivir. |
| title_fullStr | Importance of collection tube during clinical studies of oseltamivir. |
| title_full_unstemmed | Importance of collection tube during clinical studies of oseltamivir. |
| title_short | Importance of collection tube during clinical studies of oseltamivir. |
| title_sort | importance of collection tube during clinical studies of oseltamivir |
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