Importance of collection tube during clinical studies of oseltamivir.

Ex vivo conversion of the anti-influenza drug oseltamivir to its active metabolite can be inhibited by the esterase inhibitor dichlorvos or by using commercial fluoride-oxalate tubes. Oseltamivir and its active metabolite remain intact in plasma samples during a proposed virus heat inactivation step...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Lindegardh, N, Davies, G, Hien, T, Farrar, J, Singhasivanon, P, Day, N, White, N
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2007