S-adenosylmethionine in rat liver cirrhosis
An experimental model of cirrhosis in rats, by means carbon tetrachloride (CCl4) and ethanol during two months, was used to assess the effectiveness of S-adenosylmethionine. Histological studies of the liver and examination of different biochemical parameters of hepatic function were also employed....
| मुख्य लेखकों: | , , , , , |
|---|---|
| स्वरूप: | Journal article |
| भाषा: | English |
| प्रकाशित: |
1993
|
| _version_ | 1826302770750160896 |
|---|---|
| author | Cutrin, C Menino, M Carballo, C Parafita, M Perez-Becerra, E Barrio, E |
| author_facet | Cutrin, C Menino, M Carballo, C Parafita, M Perez-Becerra, E Barrio, E |
| author_sort | Cutrin, C |
| collection | OXFORD |
| description | An experimental model of cirrhosis in rats, by means carbon tetrachloride (CCl4) and ethanol during two months, was used to assess the effectiveness of S-adenosylmethionine. Histological studies of the liver and examination of different biochemical parameters of hepatic function were also employed. Bilirubin and lactic acid levels decreased significantly in the group treated with S-adenosylmethionine in comparison with the CCl4 + ethanol group. Histologic liver studies showed a significant improvement relative to fatty liver, Mallory bodies, infiltrate polymorphonuclear and perivenular fibrosis. A slight decrease in cirrhosis was observed in the animals treated with S- adenosylmethionine. |
| first_indexed | 2024-03-07T05:52:32Z |
| format | Journal article |
| id | oxford-uuid:e9635d72-c3e6-40e2-aeef-c68ad43dae12 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:52:32Z |
| publishDate | 1993 |
| record_format | dspace |
| spelling | oxford-uuid:e9635d72-c3e6-40e2-aeef-c68ad43dae122022-03-27T10:54:00ZS-adenosylmethionine in rat liver cirrhosisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e9635d72-c3e6-40e2-aeef-c68ad43dae12EnglishSymplectic Elements at Oxford1993Cutrin, CMenino, MCarballo, CParafita, MPerez-Becerra, EBarrio, EAn experimental model of cirrhosis in rats, by means carbon tetrachloride (CCl4) and ethanol during two months, was used to assess the effectiveness of S-adenosylmethionine. Histological studies of the liver and examination of different biochemical parameters of hepatic function were also employed. Bilirubin and lactic acid levels decreased significantly in the group treated with S-adenosylmethionine in comparison with the CCl4 + ethanol group. Histologic liver studies showed a significant improvement relative to fatty liver, Mallory bodies, infiltrate polymorphonuclear and perivenular fibrosis. A slight decrease in cirrhosis was observed in the animals treated with S- adenosylmethionine. |
| spellingShingle | Cutrin, C Menino, M Carballo, C Parafita, M Perez-Becerra, E Barrio, E S-adenosylmethionine in rat liver cirrhosis |
| title | S-adenosylmethionine in rat liver cirrhosis |
| title_full | S-adenosylmethionine in rat liver cirrhosis |
| title_fullStr | S-adenosylmethionine in rat liver cirrhosis |
| title_full_unstemmed | S-adenosylmethionine in rat liver cirrhosis |
| title_short | S-adenosylmethionine in rat liver cirrhosis |
| title_sort | s adenosylmethionine in rat liver cirrhosis |
| work_keys_str_mv | AT cutrinc sadenosylmethionineinratlivercirrhosis AT meninom sadenosylmethionineinratlivercirrhosis AT carballoc sadenosylmethionineinratlivercirrhosis AT parafitam sadenosylmethionineinratlivercirrhosis AT perezbecerrae sadenosylmethionineinratlivercirrhosis AT barrioe sadenosylmethionineinratlivercirrhosis |