Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)
<p><strong>Clinical Question:</strong> Does transfusing platelets to preterm infants (< 34 weeks) at a higher platelet count threshold count (< 50 x 109 /L) reduce the risk of major bleeding or death compared to only transfusing platelets when the platelet count drops...
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| Format: | Journal article |
| Language: | English |
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Wiley
2019
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| Summary: | <p><strong>Clinical Question:</strong> Does transfusing platelets to preterm infants (< 34 weeks) at a higher platelet count threshold count (< 50 x 109 /L) reduce the risk of major bleeding or death compared to only transfusing platelets when the platelet count drops below 25 x 109 /L.</p>
<p><strong>Evidence From Trial:</strong> Preterm infants with a low platelet count who were transfused platelets at the higher platelet count threshold had a higher risk of dying or having a major bleed than those who were not. The reasons why this occurred are currently unclear.</p> |
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