Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)

<p><strong>Clinical Question:</strong> Does transfusing platelets to preterm infants (&lt; 34 weeks) at a higher platelet count threshold count (&lt; 50 x 109 /L) reduce the risk of major bleeding or death compared to only transfusing platelets when the platelet count drops...

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Autor principal: Estcourt, LJ
Formato: Journal article
Idioma:English
Publicado em: Wiley 2019
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author Estcourt, LJ
author_facet Estcourt, LJ
author_sort Estcourt, LJ
collection OXFORD
description <p><strong>Clinical Question:</strong> Does transfusing platelets to preterm infants (&lt; 34 weeks) at a higher platelet count threshold count (&lt; 50 x 109 /L) reduce the risk of major bleeding or death compared to only transfusing platelets when the platelet count drops below 25 x 109 /L.</p> <p><strong>Evidence From Trial:</strong> Preterm infants with a low platelet count who were transfused platelets at the higher platelet count threshold had a higher risk of dying or having a major bleed than those who were not. The reasons why this occurred are currently unclear.</p>
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spelling oxford-uuid:e989c7ff-1900-41af-a0fa-c54d316bd1322022-03-27T10:55:04ZPlatelet transfusion thresholds in premature neonates (PlaNeT-2 trial)Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e989c7ff-1900-41af-a0fa-c54d316bd132EnglishSymplectic Elements at OxfordWiley2019Estcourt, LJ<p><strong>Clinical Question:</strong> Does transfusing platelets to preterm infants (&lt; 34 weeks) at a higher platelet count threshold count (&lt; 50 x 109 /L) reduce the risk of major bleeding or death compared to only transfusing platelets when the platelet count drops below 25 x 109 /L.</p> <p><strong>Evidence From Trial:</strong> Preterm infants with a low platelet count who were transfused platelets at the higher platelet count threshold had a higher risk of dying or having a major bleed than those who were not. The reasons why this occurred are currently unclear.</p>
spellingShingle Estcourt, LJ
Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)
title Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)
title_full Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)
title_fullStr Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)
title_full_unstemmed Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)
title_short Platelet transfusion thresholds in premature neonates (PlaNeT-2 trial)
title_sort platelet transfusion thresholds in premature neonates planet 2 trial
work_keys_str_mv AT estcourtlj platelettransfusionthresholdsinprematureneonatesplanet2trial