Multiple origins of the sickle mutation: evidence from beta S globin gene cluster polymorphisms.

Multiple origins of the sickle mutation: evidence from beta S globin gene cluster polymorphisms.

Restriction site polymorphisms of the beta globin gene cluster of 244 Jamaican beta S chromosomes have been studied. Various patterns of restriction site polymorphisms (haplotypes) both 5' and 3' to the beta gene have been found. These two groups of haplotypes were found to be non-randomiz...

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Bibliographic Details
Main Authors:	Wainscoat, J, Bell, J, Thein, S, Higgs, D, Sarjeant, G, Peto, T, Weatherall, D
Format:	Journal article
Language:	English
Published:	1983

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