Boosting BCG with MVA85A: the first candidate subunit vaccine for tuberculosis in clinical trials.

There is an urgent need for an improved vaccine against tuberculosis. Heterologous prime-boost immunization regimes induce higher levels of cellular immunity than homologous boosting with the same vaccine. Using BCG as the priming immunization in such a regime allows for the retention of the benefic...

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Autori principali: Mcshane, H, Pathan, A, Sander, C, Goonetilleke, N, Fletcher, H, Hill, A
Natura: Journal article
Lingua:English
Pubblicazione: 2005