The use of butane diacetals of glycolic acid as precursors for the synthesis of the phytotoxic calmodulin inhibitor herbarumin II
The total synthesis of phytotoxic nonenolide herbarumin II (1) has been achieved by implementation of butane diacetal (BDA)-desymmetrised glycolate building blocks. Three of the four stereogenic centres present in the key coupling fragments were generated from both enantiomeric forms of the BDA buil...
Hlavní autoři: | Diez, E, Dixon, D, Ley, S, Polara, A, Rodriguez, F |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2003
|
Podobné jednotky
-
Total synthesis of the phytotoxic agent herbarumin II using butane diacetals of glycolic acid as building blocks
Autor: Diez, E, a další
Vydáno: (2003) -
Highly diastereoselective ketone aldol reactions of butane-2,3-diacetal desymmetrised glycolic acid
Autor: Dixon, D, a další
Vydáno: (2002) -
Highly diastereoselective lithium enolate aldol reactions of butane-2,3-diacetal desymmetrized glycolic acid and deprotection to enantiopure anti-2,3-dihydroxy esters.
Autor: Dixon, D, a další
Vydáno: (2001) -
Butane-2,3-diacetal-desymmetrized glycolic acid—a new building block for the stereoselective synthesis of enantiopure α-hydroxy acids
Autor: Díez, E, a další
Vydáno: (2001) -
Studies on the generation of enolate anions from butane-2,3-diacetal protected glycolic acid derivatives and subsequent highly diastereoselective coupling reactions with aldehydes and acid chlorides
Autor: Ley, S, a další
Vydáno: (2004)