The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya.
BACKGROUND: Health facility stock-outs of artemether-lumefantrine (AL), the common first-line therapy for uncomplicated malaria across Africa, adversely affect effective malaria case-management. They have been previously reported on various scales in time and space, however the magnitude of the prob...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
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BioMed Central
2012
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| _version_ | 1826302864257974272 |
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| author | Sudoi, R Githinji, S Nyandigisi, A Muturi, A Snow, R Zurovac, D |
| author_facet | Sudoi, R Githinji, S Nyandigisi, A Muturi, A Snow, R Zurovac, D |
| author_sort | Sudoi, R |
| collection | OXFORD |
| description | BACKGROUND: Health facility stock-outs of artemether-lumefantrine (AL), the common first-line therapy for uncomplicated malaria across Africa, adversely affect effective malaria case-management. They have been previously reported on various scales in time and space, however the magnitude of the problem and trends over time are less clear. Here, 2010-2011 data are reported from public facilities in Kenya where alarming stock-outs were revealed in 2008. METHODS: Data were collected between January 2010 and June 2011 as part of 18 monthly cross-sectional surveys undertaken at nationally representative samples of public health facilities. The primary monitoring indicator was total stock-out of all four weight-specific AL packs. The secondary indicators were stock-outs of at least one AL pack and individual stock-outs for each AL pack. Monthly proportions and summary means of the proportions over the monitoring period were measured for each indicator. Stock-out trends were assessed using linear regression. RESULTS: The number of surveyed facilities across 18 time points ranged between 162 and 176 facilities. The stock-out means of the proportion of health facilities were 11.6% for total AL stock-out, 40.6% for stock-out of at least one AL pack, and between 20.5% and 27.4% for stock-outs of individual AL packs. Monthly decrease of the total AL stock-out was 0.005% (95% CI: -0.5 to +0.5; p = 0.983). Monthly decrease in the stock-out of at least one AL pack was 0.7% (95% CI: -1.5 to +0.3; p = 0.058) while stock-outs of individual AL packs decreased monthly between 0.2% for AL 24-pack and 0.7% for AL six-pack without statistical significance for any of the weight-specific packs. CONCLUSIONS: Despite lower levels of AL stock-outs compared to the reports in 2008, the stock-outs at Kenyan facilities during 2010-2011 are still substantial and of particular worry for the most detrimental:- simultaneous absence of any AL pack. Only minor decrease was observed in the stock-outs of individual AL packs. Recently launched interventions to eliminate AL stock-outs in Kenya are fully justified. |
| first_indexed | 2024-03-07T05:53:53Z |
| format | Journal article |
| id | oxford-uuid:e9da57c0-9c3d-4a8d-a2a9-e49580cbea5a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:53:53Z |
| publishDate | 2012 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:e9da57c0-9c3d-4a8d-a2a9-e49580cbea5a2022-03-27T10:57:22ZThe magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e9da57c0-9c3d-4a8d-a2a9-e49580cbea5aEnglishSymplectic Elements at OxfordBioMed Central2012Sudoi, RGithinji, SNyandigisi, AMuturi, ASnow, RZurovac, DBACKGROUND: Health facility stock-outs of artemether-lumefantrine (AL), the common first-line therapy for uncomplicated malaria across Africa, adversely affect effective malaria case-management. They have been previously reported on various scales in time and space, however the magnitude of the problem and trends over time are less clear. Here, 2010-2011 data are reported from public facilities in Kenya where alarming stock-outs were revealed in 2008. METHODS: Data were collected between January 2010 and June 2011 as part of 18 monthly cross-sectional surveys undertaken at nationally representative samples of public health facilities. The primary monitoring indicator was total stock-out of all four weight-specific AL packs. The secondary indicators were stock-outs of at least one AL pack and individual stock-outs for each AL pack. Monthly proportions and summary means of the proportions over the monitoring period were measured for each indicator. Stock-out trends were assessed using linear regression. RESULTS: The number of surveyed facilities across 18 time points ranged between 162 and 176 facilities. The stock-out means of the proportion of health facilities were 11.6% for total AL stock-out, 40.6% for stock-out of at least one AL pack, and between 20.5% and 27.4% for stock-outs of individual AL packs. Monthly decrease of the total AL stock-out was 0.005% (95% CI: -0.5 to +0.5; p = 0.983). Monthly decrease in the stock-out of at least one AL pack was 0.7% (95% CI: -1.5 to +0.3; p = 0.058) while stock-outs of individual AL packs decreased monthly between 0.2% for AL 24-pack and 0.7% for AL six-pack without statistical significance for any of the weight-specific packs. CONCLUSIONS: Despite lower levels of AL stock-outs compared to the reports in 2008, the stock-outs at Kenyan facilities during 2010-2011 are still substantial and of particular worry for the most detrimental:- simultaneous absence of any AL pack. Only minor decrease was observed in the stock-outs of individual AL packs. Recently launched interventions to eliminate AL stock-outs in Kenya are fully justified. |
| spellingShingle | Sudoi, R Githinji, S Nyandigisi, A Muturi, A Snow, R Zurovac, D The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. |
| title | The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. |
| title_full | The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. |
| title_fullStr | The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. |
| title_full_unstemmed | The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. |
| title_short | The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. |
| title_sort | magnitude and trend of artemether lumefantrine stock outs at public health facilities in kenya |
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