Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.

ग्रंथसूची विवरण
मुख्य लेखकों:	Hussein, D, Starr, A, Heikal, L, McNeill, E, Channon, K, Brown, P, Sutton, B, McDonnell, J, Nandi, M
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Wiley 2015

Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.
द्वारा: Starr, A, और अन्य
प्रकाशित: (2014)

GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
द्वारा: Tatham, A, और अन्य
प्रकाशित: (2009)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
द्वारा: Chuaiphichai, S, और अन्य
प्रकाशित: (2014)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
द्वारा: Chuaiphichai, S, और अन्य
प्रकाशित: (2014)

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
द्वारा: Ryan, B, और अन्य
प्रकाशित: (2014)

GTP cyclohydrolase II structure and mechanism.
द्वारा: Ren, J, और अन्य
प्रकाशित: (2005)

Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
द्वारा: Chuaiphichai, S, और अन्य
प्रकाशित: (2021)

GTP cyclohydrolase I deficiency results in oxidative stress and pulmonary hypertension
द्वारा: Khoo, J, और अन्य
प्रकाशित: (2004)

303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
द्वारा: Chuaiphichai, S, और अन्य
प्रकाशित: (2014)

GTP cyclohydrolase as a novel mechanism for tumour growth
द्वारा: Chen, L, और अन्य
प्रकाशित: (2015)

The protein partners of GTP cyclohydrolase I in rat organs.
द्वारा: Jianhai Du, और अन्य
प्रकाशित: (2012-01-01)

Assay for GTP Cyclohydrolase II Activity in Bacterial Extracts
द्वारा: Svetlana Yurgel, और अन्य
प्रकाशित: (2014-08-01)

Endothelial-specific GTP cyclohydrolase overexpression reduces blood pressure in salt-sensitive hypertension
द्वारा: Chen, A, और अन्य
प्रकाशित: (2006)

Decreased Cardiac Allograft Rejection in Mice Over-Expressing Human GTP Cyclohydrolase I.
द्वारा: Irina, I, और अन्य
प्रकाशित: (2009)

Cardiomyocyte-Targeted Overexpression of GTP Cyclohydrolase-1 Increases Myocyte Lusitropy and Reduces Superoxide Production
द्वारा: Carnicer, R, और अन्य
प्रकाशित: (2010)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
द्वारा: Du, Y, और अन्य
प्रकाशित: (2005)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
द्वारा: Du, Y, और अन्य
प्रकाशित: (2005)

Endotoxemia-related acute kidney injury in transgenic mice with endothelial overexpression of GTP cyclohydrolase-1.
द्वारा: Wang, W, और अन्य
प्रकाशित: (2008)

Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.
द्वारा: Liao, S, और अन्य
प्रकाशित: (2007)

Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension
द्वारा: Chen, A, और अन्य
प्रकाशित: (2005)

Control of GTP Cyclohydrolase I Activity during Aggregation of Dictyostelium discoideum
द्वारा: Ziegler Irmgard, और अन्य
प्रकाशित: (1995-08-01)

GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
द्वारा: Vanessa A. N. Kraft, और अन्य
प्रकाशित: (2019-12-01)

Functional Studies on the Promoter Region of the Human GTP Cyclohydrolase I Gene
द्वारा: Gütlich Markus, और अन्य
प्रकाशित: (1995-08-01)

Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
द्वारा: Carnicer, R, और अन्य
प्रकाशित: (2012)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
द्वारा: Adlam, D, और अन्य
प्रकाशित: (2012)

Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
द्वारा: Carnicer, R, और अन्य
प्रकाशित: (2011)

Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes.
द्वारा: Tie, L, और अन्य
प्रकाशित: (2009)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin
द्वारा: Adlam, D, और अन्य
प्रकाशित: (2012)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
द्वारा: Alp, N, और अन्य
प्रकाशित: (2003)

Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
द्वारा: Chen, A, और अन्य
प्रकाशित: (2005)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
द्वारा: Alp, N, और अन्य
प्रकाशित: (2003)

Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
द्वारा: Du, Y, और अन्य
प्रकाशित: (2008)

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
द्वारा: Alp, N, और अन्य
प्रकाशित: (2004)

Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
द्वारा: Alp, N, और अन्य
प्रकाशित: (2002)

Genetic variation in GCH1, encoding GTP-cyclohydrolase 1, regulates biopterin levels and endothelial function in atherosclerosis
द्वारा: Van, A, और अन्य
प्रकाशित: (2008)

GTP Cyclohydrolase/BH4 Pathway Protects EPC Function via Suppressing Oxidative Stress and Thrombospondin-1 in Salt-Sensitive Hypertension
द्वारा: Xie, H, और अन्य
प्रकाशित: (2009)

Nitrosative stress induced by homocysteine thiolactone drives vascular cognitive impairments via GTP cyclohydrolase 1 S-nitrosylation in vivo
द्वारा: Ya-Ling Yin, और अन्य
प्रकाशित: (2022-12-01)

Serotonergic system in vivo with [11C]DASB PET scans in GTP-cyclohydrolase deficient dopa-responsive dystonia patients
द्वारा: Elze R. Timmers, और अन्य
प्रकाशित: (2022-04-01)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
द्वारा: Alp, N, और अन्य
प्रकाशित: (2003)

Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.

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