Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.

Míreanna comhchosúla

• Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.
  de réir: Starr, A, et al.
  Foilsithe / Cruthaithe: (2014)
• GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
  de réir: Tatham, A, et al.
  Foilsithe / Cruthaithe: (2009)
• Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
  de réir: Chuaiphichai, S, et al.
  Foilsithe / Cruthaithe: (2014)
• Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
  de réir: Chuaiphichai, S, et al.
  Foilsithe / Cruthaithe: (2014)
• Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
  de réir: Ryan, B, et al.
  Foilsithe / Cruthaithe: (2014)