Placental miR-1301 is dysregulated in early-onset preeclampsia and inversely correlated with maternal circulating leptin

Introduction miRNAs are small non-coding RNAs important for the regulation of mRNA in many organs including placenta. Adipokines and specifically leptin are known to be dysregulated in preeclampsia, but little is known regarding their regulation by miRNAs during pregnancy. Methods We performed high-...

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Détails bibliographiques
Auteurs principaux: Weedon-Fekjær, MS, Sheng, Y, Sugulle, M, Johnsen, G, Herse, F, Redman, C, Lyle, R, Dechend, R, Staff, A
Format: Journal article
Langue:English
Publié: W.B. Saunders Ltd 2014