Diastereocontrolled synthesis of hydroxylated lactams
Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been observed, which appear to result either from a stereoelectronic interaction of the pyramidalised nitrogen lone pair or from steric interactions in the bicyclic system. These products can be readily deprot...
প্রধান লেখক: | , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2002
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সংক্ষিপ্ত: | Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been observed, which appear to result either from a stereoelectronic interaction of the pyramidalised nitrogen lone pair or from steric interactions in the bicyclic system. These products can be readily deprotected to give hydroxylated lactams. |
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