Diastereocontrolled synthesis of hydroxylated lactams

Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been observed, which appear to result either from a stereoelectronic interaction of the pyramidalised nitrogen lone pair or from steric interactions in the bicyclic system. These products can be readily deprot...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Andrews, MD, Brewster, A, Moloney, M
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2002