Diastereocontrolled synthesis of hydroxylated lactams

Diastereocontrolled synthesis of hydroxylated lactams

Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been observed, which appear to result either from a stereoelectronic interaction of the pyramidalised nitrogen lone pair or from steric interactions in the bicyclic system. These products can be readily deprot...

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Dettagli Bibliografici
Autori principali:	Andrews, MD, Brewster, A, Moloney, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	2002

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