Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative.

Early diagnosis and treatment with artesunate-mefloquine combination therapy (MAS) have reduced the transmission of falciparum malaria dramatically and halted the progression of mefloquine resistance in camps for displaced persons along the Thai-Burmese border, an area of low and seasonal transmissi...

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Bibliographic Details
Main Authors: Carrara, V, Sirilak, S, Thonglairuam, J, Rojanawatsirivet, C, Proux, S, Gilbos, V, Brockman, A, Ashley, E, Mcgready, R, Krudsood, S, Leemingsawat, S, Looareesuwan, S, Singhasivanon, P, White, N, Nosten, F
Format: Journal article
Language:English
Published: Public Library of Science 2006
Description
Summary:Early diagnosis and treatment with artesunate-mefloquine combination therapy (MAS) have reduced the transmission of falciparum malaria dramatically and halted the progression of mefloquine resistance in camps for displaced persons along the Thai-Burmese border, an area of low and seasonal transmission of multidrug-resistant Plasmodium falciparum. We extended the same combination drug strategy to all other communities (estimated population 450,000) living in five border districts of Tak province in northwestern Thailand.