In vitro, in silico and in vivo studies of the structure and conformational dynamics of DNA Polymerase I
DNA polymerases are a family of molecular machines involved in high-fidelity DNA replication and repair, of which DNA polymerase I (Pol) is one the best-characterized members. Pol is a strand-displacing polymerase responsible for Okazaki fragment synthesis and base-excision repair in bacteria; it co...
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| Format: | Thesis |
| Language: | English |
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2015
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