Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes.

Optimizing NMR experimental parameters for high-throughput metabolic phenotyping requires careful examination of the total biochemical information obtainable from (1)H NMR data, which includes concentration and molecular dynamics information. Here we have applied two different types of mathematical...

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Main Authors: Maher, A, Crockford, D, Toft, H, Malmodin, D, Faber, J, McCarthy, M, Barrett, A, Allen, M, Walker, M, Holmes, E, Lindon, J, Nicholson, J
格式: Journal article
语言:English
出版: 2008