Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes.

Optimizing NMR experimental parameters for high-throughput metabolic phenotyping requires careful examination of the total biochemical information obtainable from (1)H NMR data, which includes concentration and molecular dynamics information. Here we have applied two different types of mathematical...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Maher, A, Crockford, D, Toft, H, Malmodin, D, Faber, J, McCarthy, M, Barrett, A, Allen, M, Walker, M, Holmes, E, Lindon, J, Nicholson, J
Format: Journal article
Sprache:English
Veröffentlicht: 2008