Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child.

The emergence of cytotoxic T-lymphocyte (CTL) escape mutations in human immunodeficiency virus type 1 (HIV-1) proteins has been anecdotally associated with progression to AIDS, but it has been difficult to determine whether viral mutation is the cause or the result of increased viral replication. He...

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Үндсэн зохиолчид: Feeney, M, Tang, Y, Roosevelt, K, Leslie, A, McIntosh, K, Karthas, N, Walker, B, Goulder, P
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2004