Methods for specifying the target difference in a randomised controlled trial: the Difference ELicitation in TriAls (DELTA) systematic review.
BACKGROUND: Randomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified that the RCT is designed to detect. This provides reassurance that the study wil...
Main Authors: | Hislop, J, Adewuyi, T, Vale, L, Harrild, K, Fraser, C, Gurung, T, Altman, D, Briggs, A, Fayers, P, Ramsay, C, Norrie, J, Harvey, I, Buckley, B, Cook, J |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2014
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