Evaluation of a simple low-cost intervention to empower people with CKD to reduce their dietary salt intake: OxCKD1, a multicenter randomized controlled trial

<p><strong>Key Points</strong><br> •A randomized controlled trial demonstrates that a simple and cheap 1-month intervention empowers people with CKD to lower their dietary salt intake.<br> •The effect of the intervention persisted after the intervention finished.</p...

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מידע ביבליוגרפי
Main Authors: O'Callaghan, CA, Camidge, C, Thomas, R, Reschen, ME, Maycock, AJ, Lasserson, DS, Fox, RA, Thomas, NPB, Shine, B, James, T
פורמט: Journal article
שפה:English
יצא לאור: Wolters Kluwer 2023
תיאור
סיכום:<p><strong>Key Points</strong><br> •A randomized controlled trial demonstrates that a simple and cheap 1-month intervention empowers people with CKD to lower their dietary salt intake.<br> •The effect of the intervention persisted after the intervention finished.</p> <br> <p><strong>Background</strong> To evaluate the efficacy of a simple low-cost intervention to empower people with CKD to reduce their dietary salt intake.</p> <br> <p><strong>Methods</strong> A randomized controlled trial in primary and secondary care comparing the OxSalt care bundle intervention versus standard care for 1 month. Participants were people with CKD and an eGFR >20 ml/min per 1.73 m<sup>2</sup> and were recruited from primary and secondary care. The primary outcome was a reduction in dietary salt intake, as assessed by 24-hour urinary sodium excretion, after 1 month of the intervention.</p> <br> <p><strong>Results</strong> Two hundred and one participants were recruited. Dietary salt intake, as assessed from 24-hour urine sodium excretion, fell by 1.9 (±2.9) g/d in the intervention group compared with 0.4 (±2.7) g/d in the control group (<i>P</i> < 0.001). Salt intake was still reduced to a lesser extent over the following year in the intervention group.</p> <br> <p><strong>Conclusions</strong> A short, low-cost, easily delivered intervention empowers people with CKD to reduce their dietary salt intake.</p> <br> <p><strong>Trial registration</strong> ClinicalTrials.gov NCT01552317.</p>