SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections

SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections

Blood transcriptional biomarkers of acute viral infections typically reflect type 1 interferon (IFN) signalling, but it is not known whether there are biological differences in their regulation that can be leveraged for distinct translational applications. We use high frequency sampling in the SARS-...

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Bibliographic Details
Main Authors: Rosenheim, J, Gupta, RK, Thakker, C, Mann, T, Bell, LCK, Broderick, CM, Madon, K, Papargyris, L, Dayananda, P, Kwok, AJ, Greenan-Barrett, J, Wagstaffe, HR, Conibear, E, Fenn, J, Hakki, S, Lindeboom, RGH, Dratva, LM, Lemetais, B, Weight, CM, Venturini, C, Kaforou, M, Levin, M, Kalinova, M, Mann, AJ, Knight, JC
Format: Journal article
Language:English
Published: Nature Research 2024

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