HIV-1 infects macrophages by exploiting an endocytic route dependent on dynamin, Rac1 and Pak1.

Recent studies provide compelling evidence that HIV-1 entry in cell lines and lymphocytes proceeds by endocytosis, but these studies are still lacking in macrophages, an important natural target cell for HIV-1. Macrophages exhibit continual and extensive endocytic activity as part of their natural f...

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Príomhchruthaitheoirí: Carter, G, Bernstone, L, Baskaran, D, James, W
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2011