JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery.

The c-Jun N-terminal kinase (JNK) signaling pathway plays a critical role in mediating apoptosis in the developing and mature organism. The JNK signaling pathway is thought to induce apoptosis via transcription-dependent and transcription-independent mechanisms that remain to be elucidated. In this...

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Detalles Bibliográficos
Main Authors: Donovan, N, Becker, E, Konishi, Y, Bonni, A
Formato: Journal article
Idioma:English
Publicado: 2002