Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta.
AIMS/HYPOTHESIS: Protein kinase C (PKC) regulates exocytosis in various secretory cells. Here we studied intracellular translocation of the PKC isoenzymes PKCalpha and PKCdelta, and investigated how activation of PKC influences glucagon secretion in mouse and human pancreatic alpha cells. METHODS:...
المؤلفون الرئيسيون: | De Marinis, Y, Zhang, E, Amisten, S, Taneera, J, Renström, E, Rorsman, P, Eliasson, L |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2010
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مواد مشابهة
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Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.
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Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.
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Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.
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Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism.
حسب: Ding, W, وآخرون
منشور في: (1997) -
Dual effects of low and high concentrations of cAMP on glucagon secretion from mouse pancreatic A-cells
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